CHEMBL1643900


SMILES Fc1cccc(CCN[C@H]2C3C4CC5C6C4CC3C6C52)c1
InChIKey FZIIBLBHXXRTMG-RAOGCBAWSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 283.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pKi 5.35 5.35 5.35 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.74 5.74 5.74 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.12 5.12 5.12 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.15 6.15 6.15 ChEMBL
H1 HRH1 Human Histamine A pKi 5.62 5.62 5.62 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.86 5.86 5.86 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.16 5.16 5.16 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.64 5.64 5.64 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.22 5.22 5.22 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.28 5.28 5.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database