CHEMBL1688377


SMILES O=C(N1CCN(c2nccs2)CC1)C12CC3CC(CC(C3)C1)C2
InChIKey CXTMBWBHTXAOFX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 331.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pKi 6.36 6.36 6.36 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 6.36 6.36 6.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 6.2 6.2 6.2 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 6.27 6.27 6.27 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 6.27 6.27 6.27 ChEMBL