CHEMBL169889


SMILES COc1ccc(Br)cc1C1=NCC[C@H](CN2CCN(c3ccccc3)CC2)N1
InChIKey RVBVZFLMCDGFOZ-GOSISDBHSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 442.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.8 5.8 5.8 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.36 4.37 4.37 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.13 5.13 5.13 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 4.82 4.82 4.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database