CHEMBL160749


SMILES Cc1nn2c(-c3ccc(F)cc3)cccc2c1CN1CCN(c2ccc(Cl)cc2)CC1
InChIKey NSRMSZBPAQTJBS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 434.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 6.0 6.0 6.0 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.06 7.06 7.06 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.42 5.42 5.42 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.8 4.82 4.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database