CHEMBL1770373


SMILES c1ccc(Cc2ncc3c(n2)CCNCC3)cc1
InChIKey CZWQBSKNHUVZLI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 239.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.75 6.78 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Dog 5-Hydroxytryptamine A pEC50 7.97 7.97 7.97 ChEMBL
5-HT2A 5HT2A Dog 5-Hydroxytryptamine A pEC50 5.47 5.47 5.47 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pIC50 6.52 6.52 6.52 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pIC50 5.17 5.84 6.52 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pIC50 6.52 6.52 6.52 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 5.75 5.75 5.75 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 6.72 7.54 8.35 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pIC50 6.52 6.52 6.52 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.17 7.17 7.17 ChEMBL