CHEMBL1788198


SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1
InChIKey NLXASJVETPACMT-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 451.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 6.81 6.81 6.81 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.21 7.21 7.21 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.22 9.22 9.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database