Chembl1823860

Chemical Properties

SMILES O=C(NC1CCC(F)(F)CC1)N1CCC(c2nc(-c3ccc4ccccc4n3)no2)CC1
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight 441.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey HWSXWJHFTYMARD-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SMO SMO Human Frizzled F pIC50 5.82 6.07 6.32 ChEMBL