PF-03635659


SMILES CC(C)(CCC(C(N)=O)(c1ccccc1)c1ccccc1)N1CC(Oc2cccc(O)c2)C1
InChIKey WGOJWDWKHJHXSV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 444.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 9.77 9.77 9.77 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 9.94 9.94 9.94 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.7 9.79 9.89 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.86 9.86 9.86 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 9.94 9.94 9.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database