CHEMBL1940402


SMILES OC1(c2ccc(Cl)cc2)CCN(CCCCc2ccc(F)cc2)CC1
InChIKey ZTBBOIYRZHAFIN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 361.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.82 8.82 8.82 ChEMBL
D5 DRD5 Human Dopamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.98 5.98 5.98 ChEMBL
H1 HRH1 Human Histamine A pKi 6.89 6.89 6.89 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.14 6.14 6.14 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.89 6.89 6.89 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.18 6.18 6.18 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.52 6.52 6.52 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.17 6.17 6.18 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.62 7.84 8.27 ChEMBL
D2 DRD2 Human Dopamine A pKd 8.17 8.17 8.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database