CHEMBL1940406


SMILES Fc1ccc(OCCCN2CCC(c3ccc(Cl)cc3)CC2)cc1
InChIKey OPXIAQIQFMLKDK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 347.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.02 8.02 8.02 ChEMBL
D5 DRD5 Human Dopamine A pKi 6.06 6.06 6.06 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.9 6.9 6.9 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.16 6.16 6.16 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.77 6.77 6.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.39 7.39 7.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database