CHEMBL1940415


SMILES Fc1ccc(CCCCN2CCN(c3ncccn3)CC2)cc1
InChIKey GTBFEJIEYNPFMI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 314.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.21 8.21 8.21 ChEMBL
D5 DRD5 Human Dopamine A pKi 5.42 5.42 5.42 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.87 6.87 6.87 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.58 6.58 6.58 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.39 7.39 7.39 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.07 8.07 8.07 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database