AC-260584
SMILES | CCCCC1CCN(CC1)CCCN1C(=O)COc2c1ccc(c2)F |
InChIKey | BWAKMLKESHKOHK-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 0 |
Rotatable bonds | 7 |
Molecular weight (Da) | 348.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Ligand site mutations | M1 |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
M1 | ACM1 | Rat | Acetylcholine (muscarinic) | A | pIC50 | 5.9 | 5.9 | 5.9 | Guide to Pharmacology |
M1 | ACM1 | Human | Acetylcholine (muscarinic) | A | pEC50 | 7.39 | 7.39 | 7.39 | ChEMBL |
M3 | ACM3 | Human | Acetylcholine (muscarinic) | A | pEC50 | 5.23 | 5.23 | 5.23 | ChEMBL |
M5 | ACM5 | Human | Acetylcholine (muscarinic) | A | pEC50 | 6.0 | 6.0 | 6.0 | ChEMBL |