CHEMBL1802360


SMILES O=c1[nH]c2ccccc2n1C1CCN(CCCOc2ccc(F)cc2)CC1
InChIKey VNSQNNPGGZXQAN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 369.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 8.9 8.9 8.9 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.5 8.5 8.5 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.3 9.3 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pEC50 5.8 5.8 5.8 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pEC50 6.4 6.4 6.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 7.3 7.3 7.3 ChEMBL