CHEMBL182652


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(I)s2)CC1
InChIKey HBYKTDPONPUZPO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 499.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.22 6.22 6.22 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.51 7.51 7.51 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.62 8.62 8.62 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.12 7.29 7.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database