brimonidine (UK14304)



brimonidine (UK14304)


SMILES Brc1c(NC2=NCCN2)ccc2nccnc12
InChIKey XYLJNLCSTIOKRM-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 291.0

Database connections

Structure pdb 7EJ8
Ligand site mutations α2A α2B

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

brimonidine (UK14304)


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 3
Phase II 6
Phase III 12
Phase IV 21

Database connections

Structure pdb 7EJ8
Ligand site mutations α2A α2B

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score