CHEMBL2037431


SMILES Clc1ccc(N2CCN(CCCCc3nc4ccccc4s3)CC2)cc1
InChIKey SCUPEGWTGGLXHI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 385.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.4 8.4 8.4 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.48 6.48 6.48 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.72 5.72 5.72 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.21 5.21 5.21 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.04 7.04 7.04 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.88 6.88 6.88 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.66 6.66 6.66 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.51 7.51 7.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database