CHEMBL2037520


SMILES O=C(CCCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1)c1nc2ccccc2s1
InChIKey CWYDVWDIVIJIOS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 468.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 5.77 5.77 5.77 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.9 6.9 6.9 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.77 5.77 5.77 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.6 6.6 6.6 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.81 5.81 5.81 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.19 7.2 7.2 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.66 6.66 6.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database