CHEMBL2037531


SMILES O=C(CCCCN1CCC(c2ccccc2)CC1)c1nc2ccccc2s1
InChIKey CHGXPKZHRZIZSQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 378.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.97 6.97 6.97 ChEMBL
H1 HRH1 Human Histamine A pKi 7.28 7.28 7.28 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.43 5.43 5.43 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.47 8.47 8.47 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.14 8.14 8.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.19 6.19 6.19 ChEMBL
D4 DRD4 Rat Dopamine A pKi 6.75 6.75 6.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database