CHEMBL1928131


SMILES COc1ccccc1N1CCN(CCCNC(=O)c2ccc(COCCOCCOCCOCCOCCOCCOCCOCCOCc3ccc(C(=O)NCCCN4CCN(c5ccccc5OC)CC4)cc3)cc2)CC1
InChIKey FKPUMTSFODZMAY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 17
Hydrogen bond donors 2
Rotatable bonds 42
Molecular weight (Da) 1100.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 6.82 7.0 7.18 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.46 6.46 6.46 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.44 6.44 6.44 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.75 5.75 5.75 ChEMBL
α1A Q9TSW7 Pig Adrenoceptors A pKi 8.05 8.05 8.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database