CHEMBL194755


SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2ccc(F)cc2)CC1
InChIKey XOZFOKIHXFIGLO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 421.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.46 5.46 5.46 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.0 8.0 8.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.68 6.68 6.68 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.29 7.29 7.29 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.92 7.03 7.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database