CJ-042794


SMILES Clc1ccc(c(c1)C(=O)N[C@H](c1ccc(cc1)C(=O)O)C)Oc1ccc(cc1)F
InChIKey MWBNCZHVEXULBD-ZDUSSCGKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 413.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pKi 8.51 8.51 8.51 Guide to Pharmacology
EP4 PE2R4 Human Prostanoid A pKd 8.75 8.75 8.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pIC50 6.15 6.15 6.15 ChEMBL
EP4 PE2R4 Human Prostanoid A pIC50 7.42 7.87 8.18 ChEMBL