compound 10d [PMID: 34855388]


SMILES C(#N)c1cc2c(c[nH]c2c(c1)C)/C=N/NC(=N)NCCc1ccc(C(=O)OC)cc1
InChIKey XIVYUSRYHWXGLX-UVHMKAGCSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 6
Molecular weight (Da) 402.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
RXFP3 RL3R1 Human Relaxin family peptide A pKi 7.16 7.16 7.16 Guide to Pharmacology
RXFP3 RL3R1 Human Relaxin family peptide A pKi 7.16 7.16 7.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
RXFP3 RL3R1 Human Relaxin family peptide A pEC50 8.51 8.51 8.51 Guide to Pharmacology
RXFP4 RL3R2 Human Relaxin family peptide A pEC50 8.57 8.57 8.57 Guide to Pharmacology
RXFP3 RL3R1 Human Relaxin family peptide A pEC50 7.91 8.21 8.51 ChEMBL
RXFP4 RL3R2 Human Relaxin family peptide A pEC50 8.57 8.57 8.57 ChEMBL