CHEMBL1962755


SMILES COc1ccccc1N1CCN(CC2CCC(c3ccccc3)(c3ccccc3)C2=O)CC1
InChIKey GRLMWWLAYDWUKA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 440.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.85 6.85 6.85 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.4 7.4 7.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.46 8.46 8.46 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.81 6.81 6.81 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database