CHEMBL197162


SMILES O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(F)nc1
InChIKey YILNPRPYCRADTF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 424.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.89 5.89 5.89 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.0 7.0 7.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.96 8.96 8.96 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.55 7.55 7.55 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.54 7.61 7.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database