Chembl2178341

Chemical Properties

SMILES O=C(N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5)c1ccncn1
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight 448.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey JMTLZAXUTRWYOQ-QODBOBSJSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.47 6.47 6.47 ChEMBL
κ OPRK Human Opioid A pKi 8.92 8.92 8.92 ChEMBL
μ OPRM Human Opioid A pEC50 8.13 8.13 8.13 ChEMBL
μ OPRM Human Opioid A pKi 8.67 8.67 8.67 ChEMBL