CHEMBL2037522


SMILES c1ccc2c(c1)CCN(CCCCc1nc3ccccc3s1)C2
InChIKey RUTFYETZGMCUGV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 322.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.18 7.18 7.18 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.45 7.45 7.45 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.2 5.2 5.2 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.42 5.42 5.42 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.29 8.29 8.29 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.51 7.51 7.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database