CHEMBL2037524


SMILES O=C(CCCN1CCN(c2ccc(Cl)cc2)CC1)c1nc2ccccc2s1
InChIKey ZDOSDNJHLYKAPO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 399.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.7 5.7 5.7 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.08 5.08 5.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database