CHEMBL2048623


SMILES Cc1cc(OC2CCS(=O)(=O)CC2)cc(C)c1-c1cccc(COc2ccc(CCC(=O)O)c(F)c2)c1
InChIKey RPAHCZZXEGWBDL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 526.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FFA1 FFAR1 Rat Free fatty acid A pKi 8.19 8.19 8.19 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 5.12 5.12 5.12 ChEMBL
FFA1 FFAR1 Human Free fatty acid A pKi 7.8 7.8 7.8 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.91 5.91 5.91 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.03 6.03 6.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FFA1 FFAR1 Human Free fatty acid A pEC50 7.6 7.6 7.6 ChEMBL