CHEMBL2181166


SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc12
InChIKey GDRLBCZDGQFDCZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 555.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.77 5.77 5.77 ChEMBL
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 9.64 9.64 9.64 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.82 6.82 6.82 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.09 6.09 6.09 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.17 6.17 6.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database