CHEMBL2205823


SMILES COc1ccccc1CN1C2C3C4CC5C6C4C2C6C1(O)C53
InChIKey WWXCWTRLUXMAHX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.27 6.27 6.27 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.03 6.03 6.03 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.16 6.16 6.16 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.44 6.44 6.44 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.26 6.26 6.26 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.5 6.5 6.5 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.5 5.5 5.5 ChEMBL
κ OPRK Human Opioid A pKi 5.96 5.96 5.96 ChEMBL
μ OPRM Human Opioid A pKi 5.13 5.13 5.13 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.29 6.29 6.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database