CHEMBL2207632


SMILES C#Cc1cc(CN2CCN(c3ccccc3OC)CC2)c2cccccc1-2
InChIKey HNCOLMVXXZHGHT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 356.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.19 5.19 5.19 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.43 6.43 6.43 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.02 7.07 7.12 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.02 8.02 8.02 ChEMBL
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.68 5.68 5.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database