CHEMBL220900


SMILES O=C1c2c(ccc(Cl)c2Cl)[C@@H]2CNCCN12
InChIKey LGWMDPQPQYEPII-QMMMGPOBSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 256.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.16 7.16 7.16 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.97 6.97 6.97 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.24 7.24 7.24 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.7 7.7 7.7 ChEMBL