CHEMBL222814


SMILES CN1CC[C@]23c4c5ccc(O)c4O[C@H]2c2c(c4c(n2CCc2ccccc2)CCCC4)C[C@@]3(O)C1C5
InChIKey LQQGHYQRJMGRFW-XJHIRHBFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 482.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.3 8.3 8.3 ChEMBL
κ OPRK Human Opioid A pKi 6.79 6.79 6.79 ChEMBL
μ OPRM Human Opioid A pKi 7.81 7.81 7.81 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.92 7.92 7.92 ChEMBL
κ OPRK Human Opioid A pEC50 6.88 6.88 6.88 ChEMBL
μ OPRM Human Opioid A pEC50 6.76 6.76 6.76 ChEMBL