CHEMBL222864


SMILES COc1ccccc1N1CCN(CCCCC(=O)NC2CCCc3ccccc32)CC1
InChIKey COFRSTRKYJRGFB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 421.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.05 8.05 8.05 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.05 8.05 8.05 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database