galanin
SMILES | None |
InChIKey | CBSXZYWGVAQSHI-RUKUCZSXSA-N |
Sequence | GWTLNSAGYLLGPHAVGNHRSFSDKNGLTS |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Endogenous |
Approved drug | No |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GAL1 | GALR1 | Human | Galanin | A | pKi | 9.1 | 8.54 | 10.51 | Guide to Pharmacology |
GAL2 | GALR2 | Human | Galanin | A | pKi | 8.0 | 8.61 | 9.07 | Guide to Pharmacology |
GAL3 | GALR3 | Human | Galanin | A | pKi | 7.16 | 7.16 | 7.16 | Guide to Pharmacology |
GAL3 | GALR3 | Rat | Galanin | A | pKi | 7.28 | 7.28 | 7.28 | Guide to Pharmacology |
GAL2 | GALR2 | Rat | Galanin | A | pKi | 8.6 | 8.6 | 8.6 | Guide to Pharmacology |
GAL1 | GALR1 | Rat | Galanin | A | pKi | 9.22 | 9.54 | 9.85 | Guide to Pharmacology |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GAL1 | GALR1 | Human | Galanin | A | pIC50 | 9.57 | 9.73 | 9.89 | Guide to Pharmacology |
GAL2 | GALR2 | Human | Galanin | A | pEC50 | 7.91 | 8.53 | 9.15 | Guide to Pharmacology |
GAL2 | GALR2 | Human | Galanin | A | pIC50 | 9.29 | 9.29 | 9.29 | Guide to Pharmacology |
GAL3 | GALR3 | Human | Galanin | A | pIC50 | 7.12 | 7.12 | 7.12 | Guide to Pharmacology |
GAL2 | GALR2 | Rat | Galanin | A | pIC50 | 8.6 | 8.8 | 9.0 | Guide to Pharmacology |
GAL1 | GALR1 | Rat | Galanin | A | pIC50 | 10.15 | 10.19 | 10.22 | Guide to Pharmacology |
GAL1 | GALR1 | Human | Galanin | A | pIC50 | 10.1 | 10.1 | 10.1 | ChEMBL |
GAL2 | GALR2 | Human | Galanin | A | pIC50 | 8.59 | 8.59 | 8.59 | ChEMBL |