CHEMBL223896


SMILES O=C1c2c(Cl)cccc2C2CNCCN12
InChIKey QFNLHHFCTDZQJU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 222.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.23 6.23 6.23 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.51 6.51 6.51 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 5.75 5.75 5.75 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 6.3 6.3 6.3 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.43 7.43 7.43 ChEMBL