CHEMBL210717


SMILES Fc1ccccc1N1CCN(Cc2cnn(-c3ccccc3)c2)CC1
InChIKey UTUCAVNEOKJWJU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 336.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.17 6.17 6.17 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.15 9.15 9.15 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.17 7.17 7.17 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.2 7.28 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database