CHEMBL2323579


SMILES CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@@H]2c3cccc4c3c(cn4C)C[C@H]2N(C)C1
InChIKey OQPYDZQJBICVMH-SYYKKAFVSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 439.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 7.66 7.66 7.66 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 4.94 4.94 4.94 ChEMBL
D2 DRD2 Human Dopamine A pEC50 8.85 8.85 8.85 ChEMBL