CHEMBL2146811


SMILES COCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ncccc2c1=O
InChIKey SAMYTBZVLLYSKN-GOSISDBHSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 412.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.4 7.4 7.4 ChEMBL
H1 HRH1 Human Histamine A pKi 9.27 9.27 9.27 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.8 6.8 6.8 ChEMBL
H3 HRH3 Human Histamine A pKi 6.2 6.2 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database