L-365260


SMILES Cc1cccc(c1)NC(=O)NC1N=C(c2ccccc2)c2c(N(C1=O)C)cccc2
InChIKey KDFQABSFVYLGPM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 398.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Human Cholecystokinin A pKd 8.2 8.35 8.5 Guide to Pharmacology
CCK2 GASR Rat Cholecystokinin A pKi 6.13 6.13 6.13 PDSP Ki database
CCK2 GASR Mouse Cholecystokinin A pKi 6.64 6.64 6.64 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Human Cholecystokinin A pIC50 8.4 8.4 8.4 Guide to Pharmacology
CCK1 CCKAR Rat Cholecystokinin A pIC50 6.6 6.6 6.6 Guide to Pharmacology
CCK2 GASR Rat Cholecystokinin A pIC50 8.42 8.42 8.42 ChEMBL
CCK1 CCKAR Rat Cholecystokinin A pIC50 8.09 8.09 8.09 ChEMBL
CCK2 GASR Human Cholecystokinin A pIC50 8.15 8.31 8.51 ChEMBL