CHEMBL218607


SMILES CCCc1c(C(=O)NCCCCN2CCN(c3ccccc3OC)CC2)nnn1Cc1ccccc1
InChIKey UTJCXDMLSWYEJA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 490.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.52 6.52 6.52 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.96 7.96 7.96 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.24 7.71 8.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database