L741742


SMILES Clc1ccc(cc1)c1onc(c1C)C1CCN(CC1)CCc1ccccc1
InChIKey QDMAKDIDFJTXEL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 380.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.5 8.5 8.5 Guide to Pharmacology
D4 DRD4 Human Dopamine A pKi 8.46 8.48 8.6 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.11 6.15 6.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TSH TSHR Human Glycoprotein hormone A Potency 4.5 4.5 4.5 ChEMBL