CHEMBL220754


SMILES COc1ccc(Cn2nnc(C(=O)NCCCCCN3CCN(c4ccccc4OC)CC3)c2C)cc1
InChIKey NLDBOKLMUAUKIM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 506.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.57 6.57 6.57 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.06 7.06 7.06 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.03 7.03 7.03 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.77 8.17 8.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database