CHEMBL221814


SMILES c1ccc(C2CCN(Cc3cn(-c4ccccc4)nn3)CC2)cc1
InChIKey UYOTUCPKIKVHNI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 318.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.49 8.49 8.49 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.03 7.03 7.03 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.66 6.66 6.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database