lorglumide


SMILES CCCCCN(C(=O)C(NC(=O)c1ccc(c(c1)Cl)Cl)CCC(=O)O)CCCCC
InChIKey IEKOTSCYBBDIJC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 14
Molecular weight (Da) 458.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK1 CCKAR Rat Cholecystokinin A pKi 6.89 6.89 6.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Human Cholecystokinin A pIC50 5.5 5.5 5.5 Guide to Pharmacology
CCK1 CCKAR Rat Cholecystokinin A pIC50 6.7 7.45 8.2 Guide to Pharmacology
CCK2 GASR Rat Cholecystokinin A pIC50 5.52 5.52 5.52 ChEMBL
CCK1 CCKAR Guinea pig Cholecystokinin A pIC50 5.66 5.66 5.66 ChEMBL
CCK1 CCKAR Rat Cholecystokinin A pIC50 6.77 7.37 7.75 ChEMBL
CCK2 GASR Human Cholecystokinin A pIC50 4.6 5.16 5.72 ChEMBL