LXA4


SMILES CCCCC[C@@H](/C=C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)O)O
InChIKey IXAQOQZEOGMIQS-SSQFXEBMSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 14
Molecular weight (Da) 352.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FPR2/ALX FPR2 Human Formylpeptide A pKd 8.77 9.04 9.3 Guide to Pharmacology
FPR2/ALX FPRS1 Mouse Formylpeptide A pKd 8.82 8.82 8.82 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FPR2/ALX FPR2 Human Formylpeptide A pEC50 12.0 12.0 12.0 Guide to Pharmacology
GPR32 GPR32 Human A orphans A pEC50 9.7 9.7 9.7 Guide to Pharmacology
FPR2/ALX FPR2 Human Formylpeptide A pIC50 7.58 8.13 8.77 ChEMBL