CHEMBL252258


SMILES CC(=O)N1C2C=C(CN3C4CCC3CC(NC(=O)Nc3cc(F)cc(C(F)(F)F)c3)C4)CC1CCC2
InChIKey IENZWNOPOBXYDA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 508.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CXCR3 CXCR3 Mouse Chemokine A pKi 8.22 8.22 8.22 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.52 5.52 5.52 ChEMBL
CXCR3 CXCR3 Human Chemokine A pKi 8.15 8.15 8.15 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.92 5.92 5.92 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.55 6.55 6.55 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.64 6.64 6.64 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.55 6.55 6.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database