CHEMBL2336892


SMILES c1ccc(N2CCN(Cc3cnn(-c4cc5ccc4CCc4ccc(cc4)CC5)c3)CC2)cc1
InChIKey VMUIVGHGONOVFW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 448.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.77 5.79 5.82 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.35 8.47 8.6 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.64 7.67 7.7 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.46 6.96 7.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database