CHEMBL2336893


SMILES c1ccc(-n2cc(CN3CCN(c4cc5ccc4CCc4ccc(cc4)CC5)CC3)cn2)cc1
InChIKey VVPCRKVUSARVSE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 448.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.58 5.58 5.58 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.35 7.35 7.35 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.75 7.75 7.75 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.41 7.48 7.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database