CHEMBL25924


SMILES CN1CCc2cccc3c2[C@H]1Cc1cccc(-c2ccccc2)c1-3
InChIKey TVYKKVMHDGSECW-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 311.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.01 8.01 8.01 ChEMBL
D1 DRD1 Rat Dopamine A pKi 5.44 5.44 5.44 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.01 8.01 8.01 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.74 8.74 8.74 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.74 8.74 8.74 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.63 6.63 6.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database